Martes 29 de septiembre de 2026 · 151 publicaciones en las últimas 24 h · 29 fuentes · actualizado hace 9 min
Artículos recién publicados en revistas médicas con revisión por pares, de Estados Unidos, Europa y América Latina. Los preprints de medRxiv se marcan aparte: son resultados preliminares que todavía no pasan revisión por pares.
139 notas · Solo en español
To the Editor I appreciate the expanded women’s health learning opportunities provided by the JAMA Network journals under the editorial leadership of Linda Brubaker, MD, MS. The comprehensive Review of prepregnancy care and counseling by Dr Cooper and colleagues will be a valuable resource for…
To the Editor In reading the otherwise comprehensive article by Dr Cooper and colleagues on prepregnancy care and counseling, we were surprised by the lack of discussion about testing for iron deficiency. Iron deficiency, the world’s most common micronutrient deficiency, is epidemic in young women…
In Reply We thank Dr Barbieri and Drs Auerbach and DeLoughery for their comments. With regard to Barbieri’s Letter on HCV screening, the US Preventive Services Task Force recommendation is for adults aged 18 to 79 years. We agree with screening reproductive-aged female patients for…
This Perspective discusses the ethical, scientific, clinical, and manufacturing implications of excluding patients living with HIV from gene therapies for sickle cell disease.
To the Editor Dr Patel and colleagues reported that the national launch of the 988 Suicide and Crisis Lifeline was associated with an 11% reduction in adolescent and young adult suicide deaths (4372 fewer than expected). These findings suggest that a phone-based open-access crisis service…
To the Editor Dr Patel and colleagues’ recent article provided promising evidence that the 988 Suicide and Crisis Lifeline has been successful at preventing suicide death. Indeed, their results comparing “high-uptake” and “low-uptake” states are consistent with a time-series analysis of pre–988 Lifeline data that…
In Reply We thank Dr Herring and Dr Purtle for their thoughtful comments. Our study found that suicide mortality among adolescents and young adults decreased after the national launch of the 988 Lifeline, that declines were largest in states where the 988 Lifeline uptake increased…
Prostate cancer has long served as a fertile ground for innovation in cancer therapy. Compared with many other malignancies, localized prostate cancer occupies a unique clinical space. Although the incidence of new diagnoses is high, prostate cancer often follows an indolent natural history, resulting in…
This randomized clinical trial assesses whether stereotactic body radiotherapy is superior to moderately hypofractionated intensity-modulated radiation therapy in terms of patient-reported urinary irritative/obstructive and bowel quality of life and disease-free survival in patients with localized intermediate-risk prostate cancer.
The objective of this study was to assess whether stereotactic body radiotherapy (SBRT) was superior to moderately hypofractionated intensity-modulated radiation therapy (MH-IMRT) for urinary and bowel quality of life and disease-free survival in patients with localized intermediate-risk prostate cancer.
This randomized trial assesses the effect of use of total intravenous anesthesia on days alive and at home 30 days after surgery among older adults undergoing major noncardiac surgery.
This trial examined whether general anesthesia maintenance with total intravenous anesthesia (TIVA) improves patient outcomes compared with volatile-based inhalational anesthesia among adults aged ≥50 years undergoing major elective noncardiac surgery.
This JAMA Insights examines the use of nicotine pouches in the US, including adverse effects, comparisons with cigarette and e-cigarette use, and concerns regarding increased use among adolescents and young adults.
This JAMA Patient Page describes nicotine patch use, the possible harms and side effects, accidental use, and dependence.
An estimated 250 million children in low- and middle-income countries are unable to meet key developmental milestones due to biological, psychological, and social risk factors, including maternal and child malnutrition, maternal depression, and inadequate early stimulation opportunities. Without early intervention, these adversities pose threats to…
This randomized trial assesses the effect of an integrated intervention package including health, nutrition, early child stimulation, and maternal psychosocial support on weight and weight-for-age z scores among term small-for-gestational-age (SGA) infants in a low-resource setting.
This clinical trial investigated whether an integrated health, nutrition, and early stimulation intervention during infancy improves growth in term small-for-gestational-age (SGA) infants.
This JAMA Clinical Guidelines Synopsis summarizes the American College of Gastroenterology’s (ACG) 2025 clinical guideline update on management of ulcerative colitis in adults.
Alzheimer disease is defined by the accumulation of extracellular amyloid-β plaques and intraneuronal neurofibrillary tangles composed of hyperphosphorylated tau. For many years, drug development efforts have focused on amyloid-β plaques, culminating in the recent approval of the amyloid-targeting monoclonal antibodies lecanemab and donanemab for the…
This randomized clinical trial examines the efficacy and safety of the potent oral O-linked N-acetylglucosaminidase inhibitor ceperognastat in early symptomatic Alzheimer disease.
This study evaluated whether the oral O-linked N-acetylglucosaminidase inhibitor ceperognastat, at doses of 0.75 and 3 mg, compared with placebo, slows clinical progression in patients with early symptomatic Alzheimer disease with low to medium tau levels.
by Ernst Bergman, Anna Nordström, Lars Nyberg, Peter Nordström Background Type 2 diabetes incidence remains high among older adults and contributes substantially to morbidity and healthcare burden. Most evidence supporting diabetes prevention derives from intensive lifestyle interventions targeting high-risk individuals under controlled trial conditions. The…
by Gemma Whyatt, Jodi Whitehouse Rare diseases are often defined by numbers and clinical perspectives, a narrative that needs re-writing. Drawing on decades of patient advocacy, two women living with the rare condition Congenital Melanocytic Naevus argue that lived experience must shape research from the…
by Jingsong Luo, Ruiyi Liu, Jie Yin, Wangnan Cao, Shengzhi Sun, Rui Chen Background Previous studies utilizing self-reported data or polysomnography have found that poor sleep quality is associated with increased risk of morbidity and mortality. However, the association between real-world sleep patterns, including sleep…
by Brian D. Nicholson, Clare R. Bankhead, Sufen Zhu, Jason Lee Oke, Cynthia Wright Drakesmith, Rafael Perera, Frederick D. Richard Hobbs, Pradeep S. Virdee Background Unexpected weight loss (UWL) is a non-specific cancer symptom. Abnormalities in the most recent blood test contribute to cancer referral…
by Reuben Granich, Somya Gupta, Isabelle Munyangaju, Mike Ruffner Summary points In 2015, a survey-based analysis across 16 sub-Saharan African countries estimated that nearly half of people living with HIV were undiagnosed, implying ~11 million people in the region were outside the treatment cascade. However…
by Yuru Huang, Ethan C. Wolf, Andrea M. Gil, Kris Jayme G. Matas, Lisa M. Powell, Rebecca M. Schermbeck, Jennifer Falbe Background In January 2024, Perris, California, became the third jurisdiction worldwide to implement a mandatory healthy checkout policy, after Berkeley, California, and England. Healthy…
by Tianfang Shao, Mariana R. Neves, Molly Franke, Carole Mitnick, Jennifer Furin, Ted Cohen, Reza Yaesoubi Background Fluoroquinolones (FQs) are a cornerstone of most all-oral, shorter regimens endorsed by the World Health Organization for the treatment of rifampicin-resistant or multidrug-resistant tuberculosis (RR/MDR-TB). Knowledge of resistance…
by Susanna Ragnhild Andersdatter Siri, Christina Storm Mienna, Per Axelsson The General Data Protection Regulation (GDPR) provides a robust framework for regulating individual data collection, use, reuse, and storage across Europe, but offers limited safeguards for collective rights, such as those of Indigenous peoples. Here…
by Siphamandla Bonga Gumede, Jennifer Manne-Goehler, Elizabeth Kelechi Oladimeji, Nicola Bulled, Alana T. Brennan, Samanta Tresha Lalla-Edward Background Hypertension (HTN) constitutes a major and growing public health challenge in South Africa, a setting where HIV prevalence also remains high. Despite this dual burden, longitudinal evidence…
by Kevin Y. H. Liang, Thomas M. Zheng, Dandan Tan, Takayoshi Sasako, Yann Ilboudo, Yiheng Chen, Guillaume Butler-Laporte, Satoshi Yoshiji, J. Brent Richards Background Chronic kidney disease (CKD) occurs in 20–50% of the people living with Type 2 diabetes (T2D) and is the leading cause…
by Loveleen Bansi-Matharu, Daniel T. Citron, Rowan Martin-Hughes, Haroon Moolla, John Stover, Michael Pickles, Tara Mangal, Jenny Smith, Owen Mugurungi, Mmatlou Simeon Kubyana, Isaac Taramusi, Valentina Cambiano, Amon Mpofu, Debra ten Brink, Edinah Mudimu, Tsitsi Apollo, Anna Bershteyn, Linley Chewere, Dobromir Dimitrov, Stephen Macheso, Leigh…
by Jingjie Zhu, Bo Ye, Zeyu Huang, Huazhen You, Junjia Jiang, Shitong Yang, Junling Gao Background To address labor force shortages associated with population aging, many countries have proposed raising the retirement age. As health is an important determinant of employment outcomes among older workers…
by Damir Zhakparov, Nonhlanhla Lunjani, Marco Schmid, Kathleen Moriarty, Damian Roquero, Anita Dreher, Jeannette I. Heldstab-Kast, Kari C. Nadeau, Cezmi Akdis, Michael Levin, Carol Hlela, Milena Sokolowska, Liam O’Mahony, Katja Baerenfaller Background Atopic dermatitis (AD) is a chronic inflammatory skin disease that typically develops in…
by Ho Cheung William Li, Wei Xia, Joanna Yeung, Laurie Long Kwan Ho, Tan Ankie Cheung, Kai Yeung Cheung, Yiu Cheung Chan, Wai Yee Chan, Chin Wai Lui, Hong Chen Background Noncommunicable diseases (NCDs) are the leading global cause of death and are driven by…
by Zachary A. Marcum The gap between medication efficacy in trials and real-world effectiveness is widening, and with it the opportunity cost of medication nonadherence. Closing this gap requires more than individual behavior change; it requires system-level solutions, including coverage and funding design, pharmacist-led programs…
by Léa Lenglart, Luigi Titomanlio, Ilaria Alberti, Laura Almeida, Camille Aupiais, Esra Akyüz Özkan, Michael Barrett, Romain Basmaci, Ahmet Birbilen, Dorine Borensztajn, Catarina Braz Schönenberger, Silvia Bressan, Danilo Buonsenso, Teresa Campos, Susana Castanhinha, Antonio Chiaretti, Gemma Claret, Francesca De Zan, Sheena Durnin, Laszlo Fodor, Borja…
by Oliver S. Simmons, Anna Vicco, Ruth A. Martínez-Vega, José Ramos-Castañeda, Ilaria Dorigatti Background Mexico, and the Americas region more widely, have experienced increased dengue incidence in recent years, and there are concerns that the changing climate may enhance dengue virus (DENV) transmission in the…
by Karen M. Elias, Ainslie Mitchell, Eva Stadler, Timothy E. Schlub, Shanchita R. Khan, Claire Xue, Stephen J. Kent, Deborah Cromer, Miles P. Davenport, David S. Khoury Background Vaccine-induced neutralising antibodies are a well-established correlate of protection against acquisition of COVID-19. Vaccine protection from severe…
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