(MedPage Today) -- Should Medicare's annual wellness visit (AWV) be less physician-driven and more artificial intelligence (AI)-driven? That's the question being asked by CMS in its proposed physician payment rule, issued this past summer. Although...
As technology companies and governments race to advance artificial intelligence (AI), there has been a proliferation of large, energy intensive data centres. Alongside data centres’ potential to increase people’s energy costs, the facilities have also subjected a growing number of communities to a surge in…
UniQure's gene therapy continues to slow Huntington's progression after four years. But the magnitude of the benefit waned compared to a similar analysis from a year ago.
Además, se extendería por primera vez el tratamiento homogéneo de las listas a la Atención Primaria Y además: “Con la Ley de Listas de Espera será mucho más difícil tener una ‘caja B’ donde guardar pacientes”
Tener una fuerte predisposición genética a desarrollar diabetes tipo 2 no significa que todos los factores de riesgo estén fuera de nuestro control. Hay hábitos cotidianos que pueden modificar la exposición a algunos de los factores relacionados con la enfermedad.
Juristas, sanitarios, gestores, aseguradoras, industria y pacientes debatirán en Madrid sobre la regulación de la IA, los datos de salud y la responsabilidad ante las nuevas tecnologías
El desarrollo de tecnologías de Inteligencia Artificial (IA) ha generado un impacto notable en las metodologías educativas, especialmente en la educación superior (ES). Por esto, se realiza una revisión narrativa de la literatura disponible. Su influencia se refleja en la docencia, la investigación, la…
A single dose of an experimental CRISPR therapy cut LDL cholesterol and triglycerides by about half in patients with difficult-to-treat lipid disorders. The reductions were still present one year later, with the highest dose lowering LDL by 52.5% and triglycerides by 47.8%.
A major analysis suggests Phelan-McDermid syndrome, a genetic disorder closely linked to autism, may affect about 1 in 7,300 people and more than 45,000 Americans. Researchers warn that thousands of cases may remain hidden because genetic testing is often not performed, even as targeted treatments…
Researchers used CRISPR to remove CD33 from donor stem cells, potentially giving doctors a way to attack aggressive blood cancers without destroying the healthy cells patients need after a transplant. In a 30-patient trial, the edited cells successfully took hold and appeared to shield blood…
Depression is one of the most prevalent mental health disorders globally. Social media content can reflect emotional states, offering real-time signals of depressive symptoms. This study aimed to develop a deep learning model to predict depression using Twitter/X data, and to characterize potential causes of…
BackgroundRoutinely collected health data can reveal recorded care around diagnosis, but disease-specific curation does not scale across thousands of conditions. We scaled a previously developed automated framework that reduces heterogeneous clinical events into standardised, diagnosis-centred summaries of real-world care patterns. MethodsIn this retrospective observational study…
ObjectivesTo determine whether single-layer evaluation characterises clinical risk in the final note of a multilingual ambient AI scribe, and where serious errors arise. DesignTwo-arm evaluation on one common clinical-risk scale, using a frozen, reference-aligned synthetic corpus. SettingScripted consultations spanning 77 languages and five complexity levels…
Wastewater-based epidemiology (WBE) has become a valuable tool to monitor pathogens from community and municipal sources. Whereas the detection of a pathogen in wastewater can help public health agencies understand what is present in a community, it cannot provide insight into a populations preexisting immunity…
Cellular mechanisms in early Alzheimers disease (AD) remain poorly understood despite generation of extensive observational multiomic data. Weighted integration across diverse datasets can prioritise convergent mechanisms and targets. We conducted a systematic review to identify datasets profiling cell-type-specific changes in early AD. We integrated multiomic…
BackgroundEvaluating fairness in artificial intelligence (AI) is essential before clinical implementation to prevent unintended harm across diverse patient populations. This study assesses performance differences of an image-based surgical site infection (SSI) detection model across age, gender, geography, race, and skin color. MethodsModel development/validation study using…
BackgroundSchizophrenia liability reflects both the aggregate effects of many common genetic variants and rare structural variation at recurrent neurodevelopmental copy-number variant (ND-CNV) loci. Although both components of genetic liability have been associated with schizophrenia and related phenotypes, it remains unclear whether they exhibit similar neuropsychiatric…
Population-scale pathogen surveillance is limited worldwide, particularly in resource-constrained settings, where clinical systems only monitor select priority pathogens and reach only those who can access healthcare. Wastewater-based epidemiology addresses many of these gaps, offering cost-effective surveillance that is adaptable across diverse implementation contexts. In Lagos…
The ADVOCATE initiative and how autonomous AI agents could help patients with heart failure are discussed by JAMA+ AI Editor in Chief Roy Perlis, MD, MSc, and Haider Warraich, MD, a cardiologist and the program manager at ARPA-H, for the JAMA+ AI Conversations podcast.
This Perspective discusses the ethical, scientific, clinical, and manufacturing implications of excluding patients living with HIV from gene therapies for sickle cell disease.
The U.S. Food and Drug Administration today approved Fayuvi (rebisufligene etisparvovec-hopf), the first treatment for pediatric patients with mucopolysaccharidosis type IIIA (MPS IIIA), also known as Sanfilippo syndrome type A.
by Damir Zhakparov, Nonhlanhla Lunjani, Marco Schmid, Kathleen Moriarty, Damian Roquero, Anita Dreher, Jeannette I. Heldstab-Kast, Kari C. Nadeau, Cezmi Akdis, Michael Levin, Carol Hlela, Milena Sokolowska, Liam O’Mahony, Katja Baerenfaller Background Atopic dermatitis (AD) is a chronic inflammatory skin disease that typically develops in…
by Ho Cheung William Li, Wei Xia, Joanna Yeung, Laurie Long Kwan Ho, Tan Ankie Cheung, Kai Yeung Cheung, Yiu Cheung Chan, Wai Yee Chan, Chin Wai Lui, Hong Chen Background Noncommunicable diseases (NCDs) are the leading global cause of death and are driven by…
The U.S. Food and Drug Administration today authorized the Libre Duo 10 Day Continuous Dual Glucose Ketone Monitoring System for people aged 2 years and older living with diabetes.
The U.S. Food and Drug Administration today issued an accelerated approval for Genglycos (pariglasgene brecaparvovec-opnr) as the first-ever treatment for adults and children 8 years of age and older with glycogen storage disease type Ia (GSDIa)
The U.S. Food and Drug Administration today authorized the Aletta, the first standalone robotic device that can draw blood from a patient’s arm without hands-on operator intervention.
The U.S. Food and Drug Administration today issued a discussion paper on considerations for the regulation of generative artificial intelligence (GenAI)-enabled medical devices, seeking feedback from interested parties on risk assessment, premarket evaluation, postmarket monitoring, and other topics
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